Teduglutide

Product Introduction:

Product Name: Teduglutide

Product source: It is a glucagon like peptide-2 (GLP-2) analog

Content specification: ≥ 98%

CAS NO：197922-42-2

The chemical formula is C164H252N44O55S

Molecular weight: 3752.08

Detection method: HPLC

Active ingredient: Teduglutide

Product Description: White to off white freeze-dried powder

Product use: scientific research and pharmacological experiments, as well as short bowel syndrome

Product packaging: 1 gram/bottle; 10 bottles/box (customizable)

Product storage: It is recommended to store frozen at -15 ℃ to -20 ℃ and avoid direct sunlight

Shelf life: 24 months

Products  Description  

Teduglutide supplied by Xi'an Tihealth

 We use our own production line that meets international standards to synthesize high-purity raw materials specifically for pharmaceutical research and clinical applications. Strictly follow impurity control standards and comply with the Chinese Pharmacopoeia and international pharmaceutical raw material specifications. Strong batch stability, residual moisture ≤ 1.0%, endotoxin controlled within ≤ 5EU/mg, ensuring the safety of direct use in formulation production.

This product has been clinically validated to significantly improve intestinal absorption function and help patients reduce their dependence on parenteral nutrition. We provide customized packaging ranging from 1g to kg to assist customers in efficiently advancing drug research and production.

Products Function

Tedroside improves intestinal function by mimicking the action of natural GLP-2 and is mainly used for the treatment of short bowel syndrome (SBS).

Main functions:

Promote intestinal absorption, reduce dependence on parenteral nutrition, and improve intestinal barrier function

Products Application

Indications: Short bowel syndrome in adults and children

Clinical effect: After 24 weeks of treatment, 63% of adult patients showed a decrease in external nutritional requirements, while the remaining patients completely withdrew. 

Mechanism of Action

Tedroside exerts the following effects by binding to GLP-2 receptors in the intestine:

Promote intestinal growth: stimulate the proliferation of crypt cells and increase the absorption surface area of the intestine.

Release growth factors such as insulin-like growth factor (IGF-1), keratinocyte growth factor (KGF), and nitric oxide, which can repair the intestinal epithelial barrier and enhance nutrient absorption.

Inhibit gastric acid secretion: reduce gastric emptying, thereby improving intestinal function